KEY TAKEAWAYS
- The study examined whether preoperative prostate volume and enucleated weight predict short-term AEEP outcomes.
- Researchers observed that reconciling preoperative prostate volume with enucleated specimen weight enhances outcome prediction despite measurement limitations.
Prostate cancer and benign prostatic hyperplasia (BPH) are prevalent conditions affecting the prostate gland. Accurate assessment of prostate volume is crucial for effective surgical intervention.
Khi Yung Fong and the team aimed to determine if the concordance between preoperative prostate volume and enucleated weight can serve as a predictor for short-term outcomes of anatomical endoscopic enucleation of the prostate (AEEP).
They reviewed the REAP international database and analyzed 649 patients with preoperative ultrasound-derived prostate volume and enucleated specimen weight. Linear regression examined the impact of volume-weight concordance on outcomes.
Patients were grouped into 3 categories based on model residuals: less-than-expected enucleated weight, expected concordance, and more-than-expected weight. Outcomes were also assessed using only enucleated weight as a predictor, comparing those with weight ≤80 g and >80 g.
The results indicated that older patients had a more-than-expected enucleated specimen weight (P=0.006). Longer operation (P=0.012) and enucleation times (P=0.015) correlated with increased specimen weight, while postoperative acute urinary retention decreased (P=0.005).
Laser type, enucleation method, and early apical release showed no significant differences. Correlation analysis revealed that greater-than-expected prostate weight improved Qmax at 3 months. However, prostate weight alone did not significantly predict outcomes.
The study concluded that if the weight of the enucleated specimen exceeds expectations based on preoperative ultrasound volume, more remarkable Qmax improvement, and less postoperative acute urinary retention are likely. Thus, preoperative volume and enucleated weight should be interpreted together to predict outcomes.
No information regarding funds was provided.
Souce: https://pubmed.ncbi.nlm.nih.gov/39110254/
Fong KY, Gauhar V, Castellani D, et al. (2024). “Does concordance between preoperatively measured prostate volume and enucleated weight predict outcomes in endoscopic enucleation of the prostate? Results from the REAP database.” World J Urol. 2024 Aug 7;42(1):470. doi: 10.1007/s00345-024-05194-9. PMID: 39110254.
