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Meeting Coverage

Oncology meeting coverage articles from the latest medical conferences.

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Novel insights into paclitaxels role on tumor-associated macrophages in enhancing PD-1 blockade in breast cancer treatment

Novel insights into paclitaxels role on tumor-associated macrophages in enhancing PD-1 blockade in breast cancer treatment

Background Triple-negative breast cancer (TNBC) poses unique challenges due to its complex nature and the need for more effective treatments. Recent studies showed encouraging outcomes from combining paclitaxel (PTX) with programmed cell death protein-1 (PD-1) blockade …

Assessing the implications of sentinel lymph node removal in cervical cancer: an immunogenetic perspective - a SENTICOL ancillary study

Assessing the implications of sentinel lymph node removal in cervical cancer: an immunogenetic perspective - a SENTICOL ancillary study

Background Cervical cancer’s lymphatic spread primarily begins from the sentinel lymph nodes (SLNs), underlining their pivotal role in disease metastasis. However, these nodes’ immune gene expression profiles and immunoregulation mechanisms have yet to be explored. Methods Our study …

Cantharidin overcomes IL-2R{alpha} signaling-mediated vorinostat resistance in cutaneous T-cell lymphoma through reactive oxygen species

Cantharidin overcomes IL-2R{alpha} signaling-mediated vorinostat resistance in cutaneous T-cell lymphoma through reactive oxygen species

Background Vorinostat (SAHA) is a histone deacetylase inhibitor that has shown clinical efficacy against advanced cutaneous T-cell lymphoma (CTCL). However, only a subset of patients with CTCL (30–35%) respond to SAHA and the response is not …