Relevant Articles About Research and Clinical Trials in Genitourinary Cancer
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KEY TAKEAWAYS The study aimed to investigate QoL in pts with FL by LOT using the real-world data. Researchers observed worse QoL at later LOTs in FL, European pts fared worse than US pts. Follicular lymphoma (FL) is a low-grade non-Hodgkin's lymphoma (NHL) subtype...
KEY TAKEAWAYS The study aimed to evaluate the use of novel peptide-based PET tracer 68Ga-NOTA-XH05 in assessing LAG-3 expression in melanoma post-CpG oligonucleotide treatment. The study highlighted 68Ga-NOTA-XH05's potential in detecting LAG-3 and assessing...
KEY TAKEAWAYS The study aimed to investigate the clinical characteristics and outcomes of SmCC of the esophagus. Researchers noticed the need for collaborative studies to develop definitive management strategies for this rare esophageal cancer variant. Esophageal...
The LITESPARK-004 phase 2 trial aimed to conduct a post hoc pooled analysis to characterize the safety profile of belzutifan monotherapy in pts …
The phase 1 trial aimed to enhance PET imaging of HIF2alpha in pts with ccRCC with [18F]PT2977, optimizing synthesis, validation, and FDA readiness. …
The INTerpath-004 phase 2 trial aimed to assess the safety and efficacy of pembro + V940 (mRNA-4157) or placebo in pts with RCC …
Background Natural killer (NK) cell therapy is considered an attractive and safe strategy for anticancer therapy. Nevertheless, when autologous or allogenic NK cells are used alone, the clinical benefit has been disappointing. This is partially due …
Background Lenvatinib plus PD-1 inhibitors and interventional (LPI) therapy have demonstrated promising treatment effects in unresectable hepatocellular carcinoma (HCC). However, biomarkers for predicting the response to LPI therapy remain to be further explored. We aimed to …
Background Triple-negative breast cancer (TNBC) poses unique challenges due to its complex nature and the need for more effective treatments. Recent studies showed encouraging outcomes from combining paclitaxel (PTX) with programmed cell death protein-1 (PD-1) blockade …
Background Cervical cancer’s lymphatic spread primarily begins from the sentinel lymph nodes (SLNs), underlining their pivotal role in disease metastasis. However, these nodes’ immune gene expression profiles and immunoregulation mechanisms have yet to be explored. Methods Our study …