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Brain Cancer

Relevant Articles About Research and Clinical Trials in Brain Cancer

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Brain CancerNivolumabRadiation: RadiotherapyTemozolomideCompletedAustraliaAustriaBelgiumCanadaDenmarkFranceGermanyIsraelItalyJapanNetherlandsNorwayPolandRussian FederationSpainSwedenSwitzerlandUnited KingdomUnited States 0NCT02617589Phase 3CheckMate 498
An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)

An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)

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3D Illustration of a Lymphoma Virus
Lymphoma

Effective PIL vs CD Diagnosis With Radiomics & ML

KEY TAKEAWAYS The study aimed to assess the ability of radiomics combined with ML methods to differentiate PIL from CD. Researchers constructed an effective PIL vs. CD differential diagnostic model using clinical and radiologic data. Differential diagnosis of...

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Novel insights into paclitaxels role on tumor-associated macrophages in enhancing PD-1 blockade in breast cancer treatment

Novel insights into paclitaxels role on tumor-associated macrophages in enhancing PD-1 blockade in breast cancer treatment

Background Triple-negative breast cancer (TNBC) poses unique challenges due to its complex nature and the need for more effective treatments. Recent studies showed encouraging outcomes from combining paclitaxel (PTX) with programmed cell death protein-1 (PD-1) blockade …

Assessing the implications of sentinel lymph node removal in cervical cancer: an immunogenetic perspective - a SENTICOL ancillary study

Assessing the implications of sentinel lymph node removal in cervical cancer: an immunogenetic perspective - a SENTICOL ancillary study

Background Cervical cancer’s lymphatic spread primarily begins from the sentinel lymph nodes (SLNs), underlining their pivotal role in disease metastasis. However, these nodes’ immune gene expression profiles and immunoregulation mechanisms have yet to be explored. Methods Our study …

Cantharidin overcomes IL-2R{alpha} signaling-mediated vorinostat resistance in cutaneous T-cell lymphoma through reactive oxygen species

Cantharidin overcomes IL-2R{alpha} signaling-mediated vorinostat resistance in cutaneous T-cell lymphoma through reactive oxygen species

Background Vorinostat (SAHA) is a histone deacetylase inhibitor that has shown clinical efficacy against advanced cutaneous T-cell lymphoma (CTCL). However, only a subset of patients with CTCL (30–35%) respond to SAHA and the response is not …