KEY TAKEAWAYS
- The 2D-ioUS-Glio study aimed to comprehensively evaluate nn-2D-IOUS’s clinical effectiveness and surgical importance in glioma resections.
- The results demonstrated nn-2D-IOUS’s crucial role in glioma surgery, underscoring the efficacy of traditional technology, particularly in resource-constrained settings.
Amidst the rapid advancement of neurosurgical technologies, traditional tools like non-navigated two-dimensional intraoperative ultrasound (nn-2D-IOUS) face potential overshadowing, particularly in brain cancer care.
Santiago Cepeda and his team spearheaded a study that aimed to thoroughly evaluate the clinical effectiveness and surgical significance of non-navigated 2D intraoperative ultrasound (nn-2D-IOUS), particularly in glioma resection procedures.
This retrospective single-center study analyzed 99 consecutive, unselected patients diagnosed with high-grade and low-grade gliomas. The main aim was to evaluate nn-2D-IOUS proficiency in producing satisfactory image quality, detecting residual tumor tissue, and impacting resection extent. Early postoperative MRI data were used to validate findings.
The results demonstrated that the nn-2D-IOUS showed a high level of effectiveness, successfully generating good-quality images in (79%) of the patients evaluated. With a sensitivity rate of (68%) and a perfect specificity of (100%), nn-2D-IOUS unequivocally demonstrated its utility in intraoperative residual tumor detection.
When total tumor removal was the surgical objective, a resection exceeding (95%) of the initial tumor volume was achieved in (86%) of patients. Additionally, in patients where residual tumor was not detected by nn-2D-IOUS, the mean volume of undetected tumor tissue was remarkably minimal, averaging at (0.29 cm3).
The study concluded that nn-2D-IOUS plays an invaluable role in glioma surgery. The findings underscore the significance of conventional technologies in improving surgical outcomes, especially compared to advanced alternatives.
This is relevant for resource-constrained settings and underscores the importance of optimizing current tools for effective patient care. Research was sponsored by Hospital del Río Hortega and was partially funded by Instituto Carlos III.
Source: https://link.springer.com/article/10.1007/s11060-024-04614-5
Clinical Trial: https://clinicaltrials.gov/study/NCT05873946
Cepeda, S., García-García, S., Arrese, I., et al. (2024) ‘’Non-navigated 2D intraoperative ultrasound: An unsophisticated surgical tool to achieve high standards of care in glioma surgery.’’ J Neurooncol (2024). https://doi.org/10.1007/s11060-024-04614-5
