Nicholson BD, Oke J, Virdee PS, et al. Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study. Lancet Oncol 2023; 24: 733–43—In this Article, several values corresponding to the accuracy of the multi-cancer early detection tests have been updated, including changes to the Summary, Results, Discussion, and figure 3. The appendix has also been updated. These corrections have been made to the online version as of Aug 27, 2024.